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Synonym: N-Ethyl-L-glutamine; L-Glutamic acid gamma- (ethylamide) CAS: 3081-61-6
Molecular Formula: C7H14N2O3
Molecular Weight: 174.20
Botanical Source: Tea-leaves
Characteritics: In white powder form
Purity:20%,30%,99%
Melting point: 117 °C (243 °F) Major Functions: L-Theanine is an amino acid commonly found in tea (infusions of Camellia sinensis), and also in the basidiomycete mushroom Boletus badius. In 1950 the Tea laboratory of Kyoto successfully separated theanine from Gyokuro leaf, which has the highest theanine content among all teas. Theanine is related to glutamine, and can cross the blood-brain barrier. Because it can enter the brain, theanine has psychoactive properties Theanine has been shown to reduce mental and physical stress, may produce feelings of relaxation and improves cognition and mood when taken in combination with caffeine. Theanine is speculated to produce these effects by increasing the level of gamma-aminobutyric acid (GABA) production. A Theanine increase brain serotonin, dopamine, and GABA levels and has micromolar affinities for AMPA, Kainate and NMDA receptors. It has also been found that injecting spontaneously hypertensive mice with theanine significantly lowered levels of 5-hydroxyindoles in the brain Researchers also speculate that it may inhibit glutamic acid excitotoxicity. Theanine also promotes alpha wave production in the brain. Studies on test rats have shown that even repeated, extremely high doses of theanine cause little to no harmful psychological or physical effects. Theanine showed neuroprotective effects in one rat study. L-theanine may help the body's immune response to infection by boosting the disease-fighting capacity of gamma delta T cells. The study, published in 2003 by the Brigham and Women's Hospital, included a four-week trial with 11 coffee drinkers and 10 tea drinkers, who consumed 600 milliliters of coffee or black tea daily. Blood sample analysis found that the production of anti-bacterial proteins was up to five times higher in the tea-drinkers, an indicator of a stronger immune response
Dosage: Based on the alpha-wave study, a dose of 50 to 200 mg may provide a relaxation effect. No dosage of L-theanine is suggested for enhanced immune system functioning; however, volunteers in a pilot study consumed approximately 600 mL of tea a day.
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L-Theanine
